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Products >> Calcitriol CAS No 32222-06-3

Calcitriol CAS No 32222-06-3

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Description
Product Name: Calcitriol CAS No 32222-06-3
Supply Ability: 500
Related proudcts calcitriol,
Specifications 99% purity
Price Term: FOB , CNF, CIF . EXW
Port of loading: Shenzhen
Minimum Order 1G
Unit Price:

Calcitriol

***ailed Information:
Name 1α,25-Dihydroxyvitamin D3 CAS No 32222-06-3
Synonym Calcitriol
1,25-Dihydroxycholecalciferol Molecular Weight 416.64
M.F: C27H44O3 Purity 99%min
Mp 119â„?MDL Number MFCD00867079
EINECS No 250-963-8 Appearance White powder
Medicine Grade USP Grade Standard Medical stand
Model Number API Model Number API
***uments available COA,MSDS,NMR,HPLC Certificate SGS
Usage Pharmaceuticals Molecular Weight 416.64
Packing 100mg,1g,5g,25g,100g/bottle Place of origin China
Safety Description S36/37/39/S45 storage Store at -20° C,in N2, Keep from light.

Description:

Calcitriol is a metabolite of the secosteroid vitamin D3. This hormone stimulates intestinal calcium transport at a much higher rate than vitamin D3 and hydroxy D3, and is considered to represent the biologically active form of vitamin D3. In addition to regulating the movement of calcium in the blood and bone, 1α,25-Dihydroxyvitamin D3 participates in developmental regulation and signaling. It stimulates an increase in protein kinase C levels with an effect on the regulation of c-myc transcription and activation of Raf kinase. 1α,25-Dihydroxyvitamin D3 is shown to increase the synthesis of prostacyclin with a correlated increase in cyclooxygenase activity, indicating a further role in vascular regulation. 1α,25-Dihydroxyvitamin D3 (Calcitriol) is an activator of PKC and VDR.
Appearance White or almost white crystals Conform
Solubility Practically insoluble in water, freely soluble in alcohol, soluble in fatty oils Conform
Identification Infrared spectrum corresponds to that of the standard preparation Conform
The retention time of the major peak in the chromatogram corresponds to that in the chromatogram of standard preparation Conform
Related Compounds Trazoline adduct of pre-calcitriol:NMT 0.5% ND
Trans-calcitriol: NMT 0.5% 0.17%
1β-Calcitriol: NMT 0.5% ND
Any other individual impurity: NMT 0.1% Conform
Total impurities: NMT 0.1% 0.28%
Purity NLT 99.0% 99.72%
Loss on Drying NMT 0.5%

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